| Pos | LW | Peak | Wks(100) | Artist | Title | Company |
| 1 | 1 | 1 | 6 | Coez | Come nelle canzoni | Carosello Records |
| 2 | 2 | 2 | 5 | Sangiovanni & Madame | Perso nel buio | Sugar Music |
| 3 | 3 | 1 | 14 | Negramaro | Ora ti canto il mare | Sugar Music |
| 4 | 4 | 4 | 10 | LP | Angels | Energy Production |
| 5 | 6 | 3 | 15 | Madame feat. Sfera Ebbasta | Tu mi hai capito | Sugar Music |
| 6 | 7 | 6 | 10 | Bob Sinclar & Kee | D.N.A | Time Records |
| 7 | 18 | 7 | 3 | iann dior | Let You | Other |
| 8 | 5 | 4 | 9 | Ultimo | Niente | Ultimo Records |
| 9 | 8 | 1 | 15 | Francesco Gabbani | La rete | BMG/Baby Angel Music/Saifam |
| 10 | New | 10 | 1 | Ultimo | Supereroi | Ultimo Records |
| 11 | 9 | 4 | 12 | Sangiovanni | Raggi Gamma | Sugar Music |
| 12 | 15 | 12 | 2 | Il Pagante & Lorella Cuccarini | Un pacco per te | Il Pagante |
| 13 | 10 | 10 | 5 | Gazzelle | Fottuta canzone | Artist First / Maciste Dischi |
| 14 | New | 14 | 1 | Francesco Gabbani | Spazio Tempo | BMG |
| 15 | 11 | 1 | 29 | Bob Sinclar feat. Molly Hammar | We Could Be Dancing | Time Records |
| 16 | 13 | 13 | 5 | Alfie Templeman | 3D Feelings | Chess Club |
| 17 | 20 | 17 | 4 | Armin van Buuren x The Stickmen Project | No Fun | Armada Music |
| 18 | 16 | 3 | 28 | Madame | Marea | Sugar Music |
| 19 | 26 | 19 | 2 | senza_cri | A me | UtoPublishing |
| 20 | 12 | 1 | 31 | Sangiovanni | Malibu | Sugar Music |
| 21 | 14 | 12 | 5 | Sick Luke feat. Chiello & Madame | La strega del frutteto | Carosello Records |
| 22 | 19 | 5 | 21 | Oscar Anton | Ophelie | Filature |
| 23 | 17 | 8 | 12 | Alfa | Ci sarò | Artist First |
| 24 | 22 | 5 | 23 | Nu Genea feat. Célia Kameni | Marechià | Carosello Records |
| 25 | 23 | 23 | 5 | Spiller feat. Sophie Ellis-Bextor | Groovejet (2021 Purple Disco Machine & Lorenz Rhode Remix) | Defected |
| 26 | 27 | 10 | 7 | Room9 feat. Big Boy | Rollercoaster | Do It Yourself Multimedia Group |
| 27 | 28 | 13 | 14 | R3HAB & Jonas Blue feat. Ava Max & Kylie Cantrall | Sad Boy | CYB3RPVNK |
| 28 | 30 | 28 | 3 | Duran Duran feat. Tove Lo | GIVE IT ALL UP | BMG Rights Management |
| 29 | 29 | 13 | 6 | Arisa feat. Brown & Gray | Altalene | Pipshow |
| 30 | 31 | 4 | 23 | Burak Yeter | Sing Along | Time Records |
| 31 | 24 | 24 | 3 | Fly Project | En Vogue | Time Records |
| 32 | 21 | 21 | 8 | Bryan Adams | So Happy It Hurts | Bmg Rights Management |
| 33 | 32 | 11 | 13 | Imanbek & LP | Fighter | Energy Production |
| 34 | 33 | 5 | 28 | Gazzelle & Mara Sattei | Tuttecose | Maciste Dischi |
| 35 | 42 | 35 | 7 | Hugel feat. Cumbiafrica | Morenita | Cr2 Records |
| 36 | 35 | 19 | 10 | Kylie Minogue And Years & Years | A Second To Midnight | Bmg Rights Management |
| 37 | 36 | 11 | 13 | Modà | Comincia lo show | Friends & Partners srl |
| 38 | 38 | 1 | 42 | Madame | Voce | Sugar Music |
| 39 | 25 | 20 | 14 | Claptone feat. Seal | Just A Ghost | Pias |
| 40 | 34 | 7 | 19 | Ermal Meta | Stelle Cadenti | Mescal |
Nuova Radio Airplay Indipendenti: in testa Coez
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