| Pos | LW | Peak | Wks(100) | Artist | Title | Company |
| 1 | 1 | 1 | 10 | Negramaro | Ora ti canto il mare | Sugar Music |
| 2 | 6 | 2 | 2 | Coez | Come nelle canzoni | Carosello Records |
| 3 | 2 | 1 | 11 | Francesco Gabbani | La rete | BMG/Baby Angel Music/Saifam |
| 4 | 4 | 4 | 6 | LP | Angels | Energy Production |
| 5 | 5 | 4 | 5 | Ultimo | Niente | Ultimo Records |
| 6 | 3 | 3 | 11 | Madame feat. Sfera Ebbasta | Tu mi hai capito | Sugar Music |
| 7 | New | 7 | 1 | Sangiovanni & Madame | Perso nel buio | Sugar Music |
| 8 | 8 | 6 | 6 | Bob Sinclar & Kee | D.N.A | Time Records |
| 9 | 7 | 4 | 8 | Sangiovanni | Raggi Gamma | Sugar Music |
| 10 | 10 | 1 | 25 | Bob Sinclar feat. Molly Hammar | We Could Be Dancing | Time Records |
| 11 | 9 | 8 | 8 | Alfa | Ci sarò | Artist First |
| 12 | 12 | 3 | 24 | Madame | Marea | Sugar Music |
| 13 | New | 13 | 1 | Sick Luke feat. Chiello & Madame | La strega del frutteto | Carosello Records |
| 14 | 17 | 7 | 15 | Ermal Meta | Stelle Cadenti | Mescal |
| 15 | New | 15 | 1 | Gazzelle | Fottuta canzone | Artist First / Maciste Dischi |
| 16 | 16 | 13 | 10 | R3HAB & Jonas Blue feat. Ava Max & Kylie Cantrall | Sad Boy | CYB3RPVNK |
| 17 | 11 | 1 | 27 | Sangiovanni | Malibu | Sugar Music |
| 18 | 13 | 13 | 2 | Arisa feat. Brown & Gray | Altalene | Pipshow |
| 19 | 14 | 14 | 3 | Blonde Brothers | Pozzo senza fondo | Battitorumore |
| 20 | 18 | 5 | 19 | Nu Genea feat. Célia Kameni | Marechià | Carosello Records |
| 21 | 15 | 10 | 3 | Room9 feat. Big Boy | Rollercoaster | Do It Yourself Multimedia Group |
| 22 | 20 | 5 | 17 | Oscar Anton | Ophelie | Filature |
| 23 | 22 | 4 | 19 | Burak Yeter | Sing Along | Time Records |
| 24 | 19 | 11 | 9 | Modà | Comincia lo show | Friends & Partners srl |
| 25 | 21 | 11 | 9 | Imanbek & LP | Fighter | Energy Production |
| 26 | 24 | 19 | 6 | Kylie Minogue And Years & Years | A Second To Midnight | Bmg Rights Management |
| 27 | 25 | 20 | 10 | Claptone feat. Seal | Just A Ghost | Pias |
| 28 | 23 | 23 | 4 | Bryan Adams | So Happy It Hurts | Bmg Rights Management |
| 29 | 29 | 5 | 24 | Gazzelle & Mara Sattei | Tuttecose | Maciste Dischi |
| 30 | New | 30 | 1 | Alfie Templeman | 3D Feelings | Chess Club |
| 31 | New | 31 | 1 | Spiller feat. Sophie Ellis-Bextor | Groovejet (2021 Purple Disco Machine & Lorenz Rhode Remix) | Defected |
| 32 | 30 | 20 | 6 | Tears For Fears | The Tipping Point | Concorde Music Company |
| 33 | 27 | 23 | 10 | Rompasso, Imanbek feat. Karma Child | 123 (Dolly Song) | Independent |
| 34 | 33 | 1 | 38 | Madame | Voce | Sugar Music |
| 35 | 26 | 24 | 4 | Ron | Sono un figlio | Le foglie e il vento |
| 36 | 35 | 2 | 30 | Dotan | Mercy | Energy Production |
| 37 | 43 | 35 | 3 | Legno feat. Lo Stato Sociale | Che sarà mai | Artist First |
| 38 | 32 | 27 | 8 | Tom Gregory | Footprints | 3 Beat Production |
| 39 | 28 | 1 | 44 | Madame feat. Fabri Fibra | Il mio amico | Sugar Music |
| 40 | 37 | 1 | 53 | Diodato | Fino a farci scomparire | Carosello Records |
Nuova Radio Airplay Indipendenti: in testa Negramaro
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